Gene-to-Structure

Medicilon has successfully solved a large number of crystal structures both novel and known, apo and with compound soaks and co-crystallization.The results are actively used by our clients to drive their drug discovery process forward.

  1. Se-MET derivatives for X-ray crystallography or 15N, 13C labeling for NMR samples 
  2. Co-crystallization with substrates and inhibitors 
  3. 3D structural determination using molecular replacement and Se-MAD techniques